Musculosketal Symptoms and Non‐REM Sleep Disturbance in Patients with “Fibrositis Syndrome” and Healthy Subjects

@article{Moldofsky1975MusculosketalSA,
  title={Musculosketal Symptoms and Non‐REM Sleep Disturbance in Patients with “Fibrositis Syndrome” and Healthy Subjects},
  author={Harvey Moldofsky and P Scarisbrick and Robert England and H. Smythe},
  journal={Psychosomatic Medicine},
  year={1975},
  volume={37},
  pages={341–351}
}
&NA; In sleep studies of (a) patients with the “fibrositis syndrome” and (b) healthy subjects undergoing stage 4 sleep deprivation, we observed in both groups the anomalous presence of alpha‐rhythms in the non‐rapid‐eye‐movement (NREM) sleep EEG. This phenomenon has been termed alpha‐delta sleep. In the healthy subjects stage 4 deprivation was accompanied by the temporary appearance of muscoloskeletal and mood symptoms comparable to the symptoms seen chronically in the patients. It is suggested… 
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Increased frequency of wake and sleep bouts and decreased wake bout duration, together with decreased LPS and increased SWS, suggests that sleep in FM is characterized by an inability to maintain continuous sleep but a greater sleep drive compared with PI.
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