Musculoskeletal manifestations and autoimmune diseases related to new biologic agents.

  title={Musculoskeletal manifestations and autoimmune diseases related to new biologic agents.},
  author={Boulos Paul Haraoui and Edward Clark Keystone},
  journal={Current opinion in rheumatology},
  volume={18 1},
PURPOSE OF REVIEW The anti-tumor necrosis factor agents are now widely used in the management of patients with rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis and juvenile inflammatory arthritis. One of the most common observations made during their use is the development of autoantibodies. The purpose of this paper is to review this phenomenon and its clinical implications. RECENT FINDINGS While the development of different autoantibodies is a common encounter, rare cases… CONTINUE READING


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