Musculoskeletal biology and bioengineering: A new in vivo stem cell model for regenerative rheumatology

@article{McGonagle2015MusculoskeletalBA,
  title={Musculoskeletal biology and bioengineering: A new in vivo stem cell model for regenerative rheumatology},
  author={Dennis G McGonagle and Elena A. Jones},
  journal={Nature Reviews Rheumatology},
  year={2015},
  volume={11},
  pages={200-201}
}
With advances in stem cell techniques for the bioengineering and regeneration of musculoskeletal tissues comes added complexity in our understanding of stem cell biology. How will the recent discovery of a novel stem cell subset, termed osteochondroreticular stem cells, contribute to progression in the field? 
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2 Citations

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Native joint-resident mesenchymal stem cells for cartilage repair in osteoarthritis
TLDR
A proposed model in which joint-resident MSCs with access to superficial cartilage are key cells in adult cartilage repair and represent important targets for manipulation in 'chondrogenic' OA is proposed, especially in the context of biomechanical correction of joints in early disease.
Mesenchymal stem cells for cartilage repair in osteoarthritis
BACKGROUND: The degeneration of articular cartilage represents an ongoing challenge at the clinical and basic levels. Considering the restricted intrinsic capacity of resident chondrocytes to…

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