Musculocontractural Ehlers–Danlos syndrome and neurocristopathies: dermatan sulfate is required for Xenopus neural crest cells to migrate and adhere to fibronectin

@inproceedings{Gouignard2016MusculocontracturalES,
  title={Musculocontractural Ehlers–Danlos syndrome and neurocristopathies: dermatan sulfate is required for Xenopus neural crest cells to migrate and adhere to fibronectin},
  author={Nad{\`e}ge Gouignard and Marco Maccarana and Ina Strate and Kristoffer von Stedingk and Anders Malmstr{\"o}m and Edgar M Pera},
  booktitle={Disease models & mechanisms},
  year={2016}
}
Of all live births with congenital anomalies, approximately one-third exhibit deformities of the head and face. Most craniofacial disorders are associated with defects in a migratory stem and progenitor cell population, which is designated the neural crest (NC). Musculocontractural Ehlers-Danlos syndrome (MCEDS) is a heritable connective tissue disorder with distinct craniofacial features; this syndrome comprises multiple congenital malformations that are caused by dysfunction of dermatan… CONTINUE READING
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