Muscular dystrophy in the mouse: neuromuscular transmission and the concept of functional denervation.

@article{Harris1979MuscularDI,
  title={Muscular dystrophy in the mouse: neuromuscular transmission and the concept of functional denervation.},
  author={John B. Harris and Richard R Ribchester},
  journal={Annals of the New York Academy of Sciences},
  year={1979},
  volume={317},
  pages={152-70}
}
The results of recent investigations by ourselves and others indicate that no form of denervation exists to any remarkable degree in dystrophic mouse skeletal muscles. This conclusion is based on the following information: Dystrophic nerve terminals liberate normal amounts of transmitter both spontaneously and during impulse-mediated activity. The characteristics of the release process, the size of the available store of transmitter, and the probability of release of transmitter in response to… CONTINUE READING