Muscular adverse effects are common with statins

@article{Gtzsche2014MuscularAE,
  title={Muscular adverse effects are common with statins},
  author={Peter Christian G{\o}tzsche},
  journal={BMJ : British Medical Journal},
  year={2014},
  volume={348}
}
  • P. Gøtzsche
  • Published 11 June 2014
  • Medicine
  • BMJ : British Medical Journal
The 2011 Cochrane review of statins for the primary prevention of cardiovascular disease reported a risk ratio of 1.03 for muscle pain—3% more patients developed muscle pain on the drug than on placebo.1 However, industry funded randomised trials are notoriously unreliable … 
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No drug is without adverse effect potential, and fatigue and exertional intolerance are adverse effects reported by patients receiving statins.1,2 Little direct information is available regarding the
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  • F. Godlee
  • Psychology
    BMJ : British Medical Journal
  • 2014
TLDR
The BMJ and authors withdraw statements suggesting that adverse events occur in 18-20% of patients, and instead suggest that adverse event rates are more likely to be in the range of 0.1-0.5% in the general population.
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TLDR
Reductions in all-cause mortality, major vascular events and revascularisations were found with no excess of adverse events among people without evidence of CVD treated with statins, and evidence available to date showed that primary prevention with statin is likely to be cost-effective and may improve patient quality of life.
Deadly Medicines and Organised Crime: How Big Pharma Has Corrupted Healthcare
TLDR
Busting the industry myths, the business model of big pharma, Psychiatrists as drug pushers and more lies about happy pills are revealed.
Should people at low risk of cardiovascular disease take a statin?
TLDR
Statins have no overall benefit for those at low risk of cardiovascular disease and 'prescribing guidelines should not be broadened', according to the World Health Organization.