Muscle-strengthening activities are associated with lower risk and mortality in major non-communicable diseases: a systematic review and meta-analysis of cohort studies

  title={Muscle-strengthening activities are associated with lower risk and mortality in major non-communicable diseases: a systematic review and meta-analysis of cohort studies},
  author={Haruki Momma and Ryoko Kawakami and Takanori Honda and Susumu S. Sawada},
  journal={British Journal of Sports Medicine},
  pages={755 - 763}
Objective To quantify the associations between muscle-strengthening activities and the risk of non-communicable diseases and mortality in adults independent of aerobic activities. Design Systematic review and meta-analysis of prospective cohort studies. Data sources MEDLINE and Embase were searched from inception to June 2021 and the reference lists of all related articles were reviewed. Eligibility criteria for selecting studies Prospective cohort studies that examined the association between… 

Dose–response association of aerobic and muscle-strengthening physical activity with mortality: a national cohort study of 416 420 US adults

The minimum effective dose of aerobic PA for significant mortality risk reduction was 1 hour/week of MPA or VPA, with additional mortality risk Reduction observed up to 3 hours/week for older adults, and only small decreases in mortality risk were observed beyond this duration.

Aerobic or Muscle-Strengthening Physical Activity: Which Is Better for Health?

This review will clarify the relative benefits of MSPA versus MVPA on health-related outcomes to determine the best type of PA for health.

Muscle-strengthening activities to improve health outcomes: what the evidence supports

Research has found musclestrengthening activities are independently associated with a variety of improved health outcomes including decreases in allcause mortality, and improvements in cardiometabolic and mental health.

Ageing with Interstitial lung disease: preserving health and well being

The development of a prediction score is proposed to classify those at risk of frailty in ILD and guide interventions that preserve successful ageing for all levels of ILD severity.

The Functional Role of Long Non-Coding RNA in Myogenesis and Skeletal Muscle Atrophy

Recent knowledge on the regulatory roles of lncRNAs in skeletal muscle atrophy is reviewed and the issues and possibilities of targeting lnc RNAs as a treatment for skeletal Muscle wasting disorders in humans are discussed.

‘A Lot of People Just Go for Walks, and Don’t Do Anything Else’: Older Adults in the UK Are Not Aware of the Strength Component Embedded in the Chief Medical Officers’ Physical Activity Guidelines—A Qualitative Study

Strength recommendations have been embedded within the UK’s Chief Medical Officers’ physical activity guidelines since 2011. In 2019, they were given a more prominent position in the accompanying

Adherence to aerobic and muscle-strengthening activities guidelines: a systematic review and meta-analysis of 3.3 million participants across 31 countries

Only one out of five adolescents and adults met the recommended combined aerobic and MSA guidelines, and large-scale public health interventions promoting both types of exercise are needed to reduce the associated burden of non-communicable diseases.


  • Medicine
    The Nurse practitioner
  • 2022



Muscle-strengthening activities and cancer incidence and mortality: a systematic review and meta-analysis of observational studies

Muscle-strengthening activities were associated with reduced incidence of kidney cancer and total cancer mortality, and combined muscle-Strengthening and aerobic activities may provide a greater reduction in totalcancer mortality.

Muscle‐strengthening activities and risk of cardiovascular disease, type 2 diabetes, cancer and mortality: A review of prospective cohort studies

The evidence supports engaging in 1-2 sessions per week of muscle-strengthening activities, preferably performed complementary to the recommended levels of aerobic MVPA, up to 2.5 total per week, although data are limited, caution is suggested for training exceeding 2.

Independent and joint associations between leisure time physical activity and strength activities with mortality outcomes in older adults ≥65 years-of-age: a prospective cohort study.

Investigating the associations between recommended physical activity and mortality in older adults ≥65 years-of-age found that engaging in muscle-strengthening activity ≥2 times/week may provide additional benefits among physically active older adults.

Muscle-strengthening physical activity is associated with cancer mortality: results from the 1998–2011 National Health Interview Surveys, National Death Index record linkage

Adhering to the U.S. federal guideline for MSA is associated with lower cancer mortality and public health programs and policy for cancer prevention and control should promote MSA to further reduce cancer mortality.

Relationship Between Muscle-Strengthening Activity and Cause-Specific Mortality in a Large US Cohort

Engaging in ≥2 hours per week of MSA was associated with lower all-cause mortality, independent of aerobic activity, and this findings support recommending muscle-strengthening activities for overall health.

Recommended physical activity and all cause and cause specific mortality in US adults: prospective cohort study

Adults who engage in leisure time aerobic and muscle strengthening activities at levels recommended by the 2018 physical activity guidelines for Americans show greatly reduced risk of all cause and cause specific mortality.

The association of resistance training with mortality: A systematic review and meta-analysis

Resistance training is associated with lower mortality and appears to have an additive effect when combined with aerobic exercise, according to a meta-analysis.