Muscle strength response to strength training is influenced by insulin-like growth factor 1 genotype in older adults.

@article{Kostek2005MuscleSR,
  title={Muscle strength response to strength training is influenced by insulin-like growth factor 1 genotype in older adults.},
  author={Matthew C. Kostek and Matthew J. Delmonico and Jonathan Reichel and Stephen M Roth and Larry Douglass and Robert E. Ferrell and Ben F. Hurley},
  journal={Journal of applied physiology},
  year={2005},
  volume={98 6},
  pages={2147-54}
}
Strength training (ST) is considered an intervention of choice for the prevention and treatment of sarcopenia. Reports in the literature have suggested that the insulin-like growth factor I protein (IGF-I) plays a major role in ST-induced skeletal muscle hypertrophy and strength improvements. A microsatellite repeat in the promoter region of the IGF1 gene has been associated with IGF-I blood levels and phenotypes related to IGF-I in adult men and women. To examine the influence of this… CONTINUE READING

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