Muscle ring finger 1, but not muscle ring finger 2, regulates cardiac hypertrophy in vivo.

@article{Willis2007MuscleRF,
  title={Muscle ring finger 1, but not muscle ring finger 2, regulates cardiac hypertrophy in vivo.},
  author={Monte S Willis and Christopher Ike and Luge Li and Da-zhi Wang and David J Glass and C. G. Patterson},
  journal={Circulation research},
  year={2007},
  volume={100 4},
  pages={456-9}
}
Muscle ring finger (MuRF) proteins have been implicated in transmitting mechanical forces to cell signaling pathways through their interactions with the giant protein titin. Recent evidence has linked mechanically-induced stimuli with the control of serum response factor activity and localization through MuRF2. This observation is particularly intriguing in… CONTINUE READING