Muscle cytoskeletal disruption occurs within the first 15 min of cyclic eccentric contraction.

@article{Lieber1996MuscleCD,
  title={Muscle cytoskeletal disruption occurs within the first 15 min of cyclic eccentric contraction.},
  author={Richard L. Lieber and Lars Eric Thornell and Jan Frid{\'e}n},
  journal={Journal of applied physiology},
  year={1996},
  volume={80 1},
  pages={
          278-84
        }
}
The time course of loss of the 55,000-Da intermediate filament protein desmin was measured in rabbit muscles subjected to cyclic eccentric contraction. Rabbit extensor digitorum longus (EDL) and tibialis anterior (TA) muscles were examined 5 or 15 min after eccentric exercise and 1 h or 1 day after 30 min of an eccentric exercise protocol (n = 16 rabbits). The earliest change noted was a significant loss of desmin labeling in 2.5 +/- 0.63% of the rabbit EDL muscle fibers (P < 0.005) 5 min after… CONTINUE READING
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