Muscle biopsy substantiates long-term MRI alterations one year after a single dose of botulinum toxin injected into the lateral gastrocnemius muscle of healthy volunteers.

@article{Schroeder2009MuscleBS,
  title={Muscle biopsy substantiates long-term MRI alterations one year after a single dose of botulinum toxin injected into the lateral gastrocnemius muscle of healthy volunteers.},
  author={A. Sebastian Schroeder and Birgit Ertl-Wagner and Stefanie Britsch and J. M. Schr{\"o}der and Stefan Nikolin and Joachim Weis and Wolfgang M{\"u}ller-Felber and Inga K Koerte and Maximilian Stehr and Steffen Berweck and Ingo Borggraefe and Florian R. Heinen},
  journal={Movement disorders : official journal of the Movement Disorder Society},
  year={2009},
  volume={24 10},
  pages={1494-503}
}
Despite numerous clinical and experimental studies on botulinum toxin type A (BoNT/A), long-term alterations of muscle texture and fine structure following BoNT/A treatment have thus far not been studied in normal human skeletal muscle. After obtaining institutional review board approval, we performed a prospective, placebo-controlled, double-blinded follow-up study on two healthy adults using magnetic resonance imaging (MRI) and muscle biopsy to visualize long-term alterations after a single… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 26 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 50 references

Long-term efficacy of intraglandular botulinum toxin injection to 1501 BoNT WITHIN THE MUSCLE

  • AS Schroeder, T Kling, I Borggaefe, F Heinen, S. Berweck
  • Movement Disorders,
  • 2009

Similar Papers

Loading similar papers…