Muscle atrophy in chronic kidney disease results from abnormalities in insulin signaling.

@article{Price2010MuscleAI,
  title={Muscle atrophy in chronic kidney disease results from abnormalities in insulin signaling.},
  author={Stephen R. Price and Jennifer L. Gooch and Sue K. Bolitho Donaldson and Tiffany K Roberts-Wilson},
  journal={Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation},
  year={2010},
  volume={20 5 Suppl},
  pages={S24-8}
}
Muscle atrophy is a significant consequence of chronic kidney disease that increases a patient's risk of mortality and decreases their quality of life. The loss of lean body mass results, in part, from an increase in the rate of muscle protein degradation. In this review, the proteolytic systems that are activated during chronic kidney disease and the key insulin signaling pathways that regulate the protein degradative processes are described. 
11 Citations
23 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 11 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 23 references

Similar Papers

Loading similar papers…