Muscle atonia is triggered by cholinergic stimulation of the basal forebrain: implication for the pathophysiology of canine narcolepsy

@inproceedings{Nishino1995MuscleAI,
  title={Muscle atonia is triggered by cholinergic stimulation of the basal forebrain: implication for the pathophysiology of canine narcolepsy},
  author={Seiji Nishino and Mehdi Tafti and Marion S. Reid and J Shelton and Jerome M Siegel and William C. Dement and Emmanuel Mignot},
  booktitle={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={1995}
}
  • Seiji Nishino, Mehdi Tafti, +4 authors Emmanuel Mignot
  • Published in
    The Journal of neuroscience…
    1995
  • Medicine, Biology
  • Narcolepsy is a sleep disorder characterized by excessive daytime sleepiness and rapid eye movement (REM) sleep-related symptoms, such as cataplexy. The exact pathophysiology underlying the disease is unknown but may involve central cholinergic systems. It is known that the brainstem cholinergic system is activated during REM sleep. Furthermore, REM sleep and REM sleep atonia similar to cataplexy can be triggered in normal and narcoleptic dogs by stimulating cholinergic receptors within the… CONTINUE READING

    Citations

    Publications citing this paper.
    SHOWING 1-10 OF 53 CITATIONS, ESTIMATED 53% COVERAGE

    Narcolepsy and depression and the neurobiology of gammahydroxybutyrate

    VIEW 5 EXCERPTS
    CITES BACKGROUND
    HIGHLY INFLUENCED

    Clinical and neurobiological aspects of narcolepsy.

    VIEW 2 EXCERPTS
    CITES BACKGROUND

    Basal forebrain acetylcholine release during REM sleep is significantly greater than during waking.

    VIEW 4 EXCERPTS
    CITES RESULTS & BACKGROUND
    HIGHLY INFLUENCED

    Neurobiology of waking and sleeping.

    VIEW 2 EXCERPTS
    CITES BACKGROUND

    FILTER CITATIONS BY YEAR

    1996
    2020

    CITATION STATISTICS

    • 2 Highly Influenced Citations

    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 94 REFERENCES

    Dopamine D2 mechanisms in canine narcolepsy

    Medullary regions mediating atonia

    • Ya Yun Lai, Jerome M Siegel
    • Biology, Medicine
    • The Journal of neuroscience : the official journal of the Society for Neuroscience
    • 1988