Muscle RING-finger protein-1 (MuRF1) as a connector of muscle energy metabolism and protein synthesis.

Abstract

During pathophysiological muscle wasting, a family of ubiquitin ligases, including muscle RING-finger protein-1 (MuRF1), has been proposed to trigger muscle protein degradation via ubiquitination. Here, we characterized skeletal muscles from wild-type (WT) and MuRF1 knockout (KO) mice under amino acid (AA) deprivation as a model for physiological protein… (More)
DOI: 10.1016/j.jmb.2007.11.049

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Cite this paper

@article{Koyama2008MuscleRP, title={Muscle RING-finger protein-1 (MuRF1) as a connector of muscle energy metabolism and protein synthesis.}, author={Suguru Koyama and Shoji Hata and Christian C. Witt and Yasuko Ono and Stefanie Lerche and Koichi Ojima and Tomoki Chiba and Naoko Doi and Fujiko Kitamura and Keiji Tanaka and Keiko Abe and Stephanie H. Witt and Vladimir Rybin and Alexander Gasch and Thomas Franz and Siegfried Labeit and Hiroyuki Sorimachi}, journal={Journal of molecular biology}, year={2008}, volume={376 5}, pages={1224-36} }