Muscimol inhibition of medullary raphé neurons decreases the CO2 response and alters sleep in newborn piglets.

@article{Messier2002MuscimolIO,
  title={Muscimol inhibition of medullary raph{\'e} neurons decreases the CO2 response and alters sleep in newborn piglets.},
  author={Michelle L Messier and A. -Y. Li and Eugene Edward Nattie},
  journal={Respiratory physiology & neurobiology},
  year={2002},
  volume={133 3},
  pages={197-214}
}
Medullary raphé neurons are chemosensitive in vitro (Wang et al., J. Physiol. Lond. 511 (1998)), are involved in the ventilatory response to CO(2) in vivo (Dreshaj et al., Respir. Physiol. 111 (1998); Nattie and Li, J. Appl. Physiol. 90 (2001)), and are abnormal in many Sudden Infant Death Syndrome (SIDS) victims (Panigrahy et al., J. Neuropathol. Exp. Neurol. 59 (2000)). In this study we determine whether the ventilatory response to CO(2) is altered when medullary raphé neuronal function is… CONTINUE READING

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