Muscarinic receptor subtype determines vulnerability to oxidative stress in COS-7 cells.

@article{Joseph2002MuscarinicRS,
  title={Muscarinic receptor subtype determines vulnerability to oxidative stress in COS-7 cells.},
  author={James Joseph and Derek R. Fisher and Joseph Strain},
  journal={Free radical biology & medicine},
  year={2002},
  volume={32 2},
  pages={
          153-61
        }
}
Research has suggested that there may be increased brain-region selective vulnerability to oxidative stress in aging and that Vulnerability to oxidative stress may be important in determining regional differences in neuronal aging. We assessed whether one factor determining vulnerability to oxidative stress might involve qualitative/quantitative differences in receptor subtypes in various neuronal populations. COS-7 cells were transfected with one of five muscarinic receptor subtypes (M1-M5… CONTINUE READING
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