Muscarinic blockade of methacholine induced airway and parenchymal lung responses in anaesthetised rats.

Abstract

BACKGROUND It has previously been shown that M1 cholinergic receptors are involved in the parenchymal response to inhaled methacholine in puppies using the M1 selective antagonist pirenzepine. Although M3 receptors are responsible for acetylcholine induced bronchoconstriction in isolated rat lung, the role of M1 receptors has not been determined in the rat… (More)

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Cite this paper

@article{Tulic1999MuscarinicBO, title={Muscarinic blockade of methacholine induced airway and parenchymal lung responses in anaesthetised rats.}, author={Meri Katarina Tulic and Janet L. Wale and Ferenc Pet{\'a}k and Peter D. Sly}, journal={Thorax}, year={1999}, volume={54 6}, pages={531-7} }