Muscarinic (m2/m4) receptors reduce N- and P-type Ca2+ currents in rat neostriatal cholinergic interneurons through a fast, membrane-delimited, G-protein pathway.

@article{Yan1996MuscarinicR,
  title={Muscarinic (m2/m4) receptors reduce N- and P-type Ca2+ currents in rat neostriatal cholinergic interneurons through a fast, membrane-delimited, G-protein pathway.},
  author={Zhen Yan and D. James Surmeier},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={1996},
  volume={16 8},
  pages={2592-604}
}
The signaling pathways mediating the muscarinic modulation of Ca2+ currents in neostriatal cholinergic interneurons were studied by combined patch-clamp recording and single-cell reverse transcription-PCR. Cholinergic interneurons were identified by the presence of choline acetyltransferase mRNA. These neurons expressed Q-, N-, L-, P-, and R-type Ca2+ currents and the mRNA for the alpha1 subunits believed to form the channels underlying these currents (classes A, B, C, D, and E). Of the… CONTINUE READING
Highly Influential
This paper has highly influenced 14 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 74 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 75 references

Microcircuitry of the neostriatum

  • JP Bolam, BD Bennett
  • Molecular and cellular mechanisms of the…
  • 1995
Highly Influential
5 Excerpts

Muscarinic receptor sub - tvoes

  • EC Hulme, NJ Birdsall, NJ Buckley
  • Annu Rev Pharmacol Toxic 01
  • 1990
Highly Influential
9 Excerpts

Similar Papers

Loading similar papers…