Muscarine modulation by a G-protein alpha-subunit of delayed rectifier K+ current in rat ventromedial hypothalamic neurones.

@article{FfrenchMullen1994MuscarineMB,
  title={Muscarine modulation by a G-protein alpha-subunit of delayed rectifier K+ current in rat ventromedial hypothalamic neurones.},
  author={Jarlath M H Ffrench-Mullen and Carlos Plata-Salam{\'a}n and Noel J. Buckley and P Danks},
  journal={The Journal of physiology},
  year={1994},
  volume={474 1},
  pages={21-6}
}
1. Rat cultured ventromedial hypothalamic (VMH) neurones obtained from embryonic hypothalamus were used to study the muscarinic (carbachol) modulation of voltage-gated K+ currents with the whole-cell patch-clamp technique. 2. Carbachol produced a potent and concentration-dependent (100 fM to 100 microM) decrease of the outward delayed rectifier K+ current… CONTINUE READING