Musashi1 RNA-binding protein regulates oligodendrocyte lineage cell differentiation and survival.

@article{Dobson2008Musashi1RP,
  title={Musashi1 RNA-binding protein regulates oligodendrocyte lineage cell differentiation and survival.},
  author={Nicole R. Dobson and Yong-xing Zhou and Nicole C Flint and Regina C Armstrong},
  journal={Glia},
  year={2008},
  volume={56 3},
  pages={318-30}
}
Expression of Musashi1 (Msi1), an evolutionarily conserved RNA-binding protein, in neural stem cells of the subventricular zone in the postnatal and adult CNS indicates a potential role in the generation of oligodendrocytes. We now show Msi1 expression in a subset of oligodendrocyte progenitor (OP) cells in white matter areas temporally and spatially associated with oligodendrogenesis in the postnatal CNS. Msi1 function was evaluated by infection of OP cells with retroviral transduction of Msi1… CONTINUE READING

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