Murine uterine decidualization is a novel function of autoimmune regulator-beyond immune tolerance.

@article{Soumya2016MurineUD,
  title={Murine uterine decidualization is a novel function of autoimmune regulator-beyond immune tolerance.},
  author={Vasanthi Soumya and Renjini Ambika Padmanabhan and Shiny Titus and Malini Laloraya},
  journal={American journal of reproductive immunology},
  year={2016},
  volume={76 3},
  pages={224-34}
}
PROBLEM Autoimmune polyendocrinopathy, candidiasis, and ectodermal dystrophy (APECED, APS-1) patients characterized by Aire (autoimmune regulator) mutations and Aire homozygous knockouts (Aire(-/-) ) exhibit infertility. It is not clear as to what contributes to infertility in the above. METHOD OF STUDY This study investigates the expression of "AIRE in… CONTINUE READING