Murine thymocyte and splenocyte Ia antigens are indistinguishable by two-dimensional gel electrophoresis.

Ia antigens have been found on the surface of B lymphocytes, macrophages, epidermal Langerhans cells and on certain transformed cells. Ia antigens have also been detected on the surface of thymocytes but the biosynthesis of these antigens by thymocytes has been difficult to demonstrate. We describe the labeling of murine thymocytes with 35S-methionine and… CONTINUE READING