Murine prenatal expression of cholecystokinin in neural crest, enteric neurons, and enteroendocrine cells.

@article{Lay1999MurinePE,
  title={Murine prenatal expression of cholecystokinin in neural crest, enteric neurons, and enteroendocrine cells.},
  author={Jean M. Lay and Patrick J. Gillespie and Linda C. Samuelson},
  journal={Developmental dynamics : an official publication of the American Association of Anatomists},
  year={1999},
  volume={216 2},
  pages={190-200}
}
Cholecystokinin (CCK) is a regulatory peptide that is primarily expressed in two adult cell types: endocrine cells of the intestine and neurons of the central nervous system. To determine the ontogeny of CCK expression during intestinal organogenesis, we created a mouse strain in which the CCK gene was replaced by a lacZ reporter cassette using homologous recombination in embryonic stem cells. Initially, CCK expression in the developing intestine was limited to the myenteric plexus of the… CONTINUE READING

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