Murine motor neuron disease (the wobbler mouse): degeneration and regeneration of the lower motor neuron.

@article{Mitsumoto1982MurineMN,
  title={Murine motor neuron disease (the wobbler mouse): degeneration and regeneration of the lower motor neuron.},
  author={Hiroshi Mitsumoto and Walter G. Bradley},
  journal={Brain : a journal of neurology},
  year={1982},
  volume={105 (Pt 4)},
  pages={811-34}
}
The study of the temporospatial pattern of lower motor neuronal generation in the wr/wr mouse demonstrated that the pathological changes started in the neuronal perikaryon in the spinal cord. Thus the wr/wr mouse suffers from a primary motor neuronopathy. Axonal pathology predominated at the level of the ventral root and suggested a focal proximal… CONTINUE READING