Murine lung eosinophil activation and chemokine production in allergic airway inflammation

@article{Rose2010MurineLE,
  title={Murine lung eosinophil activation and chemokine production in allergic airway inflammation},
  author={Christopher Edward Rose and Joanne A. Lannigan and Paul Hyungmin Kim and James Joseph Lee and Shu Man Fu and Sun-sang Joseph Sung},
  journal={Cellular and Molecular Immunology},
  year={2010},
  volume={7},
  pages={361-374}
}
Eosinophils play important roles in asthma and lung infections. Murine models are widely used for assessing the functional significance and mechanistic basis for eosinophil involvements in these diseases. However, little is known about tissue eosinophils in homeostasis. In addition, little data on eosinophil chemokine production during allergic airway inflammation are available. In this study, the properties and functions of homeostatic and activated eosinophils were compared. Eosinophils from… CONTINUE READING

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