Murine leukemia virus reverse transcriptase: structural comparison with HIV-1 reverse transcriptase.

@article{Cot2008MurineLV,
  title={Murine leukemia virus reverse transcriptase: structural comparison with HIV-1 reverse transcriptase.},
  author={Marie L. Cot{\'e} and Monica J Roth},
  journal={Virus research},
  year={2008},
  volume={134 1-2},
  pages={186-202}
}
Recent X-ray crystal structure determinations of Moloney murine leukemia virus reverse transcriptase (MoMLV RT) have allowed for more accurate structure/function comparisons to HIV-1 RT than were formerly possible. Previous biochemical studies of MoMLV RT in conjunction with knowledge of sequence homologies to HIV-1 RT and overall fold similarities to RTs in general, provided a foundation upon which to build. In addition, numerous crystal structures of the MoMLV RT fingers/palm subdomain had… CONTINUE READING

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The crystal structure of the monomeric reverse transcriptase from Moloney murine leukemia virus

  • M. Georgiadis
  • 2004
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