Murine infection model for maintenance and amplification of Cryptosporidium parvum oocysts.

@article{Petry1995MurineIM,
  title={Murine infection model for maintenance and amplification of Cryptosporidium parvum oocysts.},
  author={Franz Petry and Heidi A. Robinson and Vincent McDonald},
  journal={Journal of clinical microbiology},
  year={1995},
  volume={33 7},
  pages={1922-4}
}
Propagation of Cryptosporidium parvum is problematic because in vitro development of the parasite is poor and animals are only briefly susceptible as neonates. At present oocysts of the parasite are usually procured by passage in neonatal sheep or cattle. In the present study, large numbers of oocysts of C. parvum could be isolated following infection of dexamethasone-treated adult C57BL/6 mice. The amount of immunosuppressive drug and the regimen of administration were critical for successful… CONTINUE READING