Murine immune responses to Neisseria meningitidis group C capsular polysaccharide and a thymus-dependent toxoid conjugate vaccine.

@article{Rubinstein1998MurineIR,
  title={Murine immune responses to Neisseria meningitidis group C capsular polysaccharide and a thymus-dependent toxoid conjugate vaccine.},
  author={Leonard J Rubinstein and Pablo A. Garcia-Ojeda and Francis Michon and Harold J. Jennings and Kathryn E. Stein},
  journal={Infection and immunity},
  year={1998},
  volume={66 11},
  pages={5450-6}
}
The polysaccharide (PS) capsules of many pathogenic bacteria are poor immunogens in infants and young children as a result of the delayed response to PS antigens during ontogeny. The development of polysaccharide-protein conjugate vaccines for Haemophilus influenzae type b, which have proven to be efficacious in this age group, has led to active development by a number of investigators of conjugate vaccines for other diseases. We describe here the response of several mouse strains to the… CONTINUE READING
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Phase I evaluation of a meningococcal C-tetanus toxoid conjugate vaccine

  • P. Richmond, D. Goldblatt, P. Fusco, J. Fusco, I. Heron, F. Michon
  • abstr. G-111,
  • 1997
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