Murine hepatocellular carcinoma derived stem cells reveal epithelial-to-mesenchymal plasticity

Abstract

AIM To establish a model to enrich and characterize stem-like cells from murine normal liver and hepatocellular carcinoma (HCC) cell lines and to further investigate stem-like cell association with epithelial-to-mesenchymal transition (EMT). METHODS In this study, we utilized a stem cell conditioned serum-free medium to enrich stem-like cells from mouse… (More)
DOI: 10.4252/wjsc.v9.i9.159

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