Murine gammaherpesvirus-68 glycoprotein H-glycoprotein L complex is a major target for neutralizing monoclonal antibodies.

@article{Gill2006MurineGG,
  title={Murine gammaherpesvirus-68 glycoprotein H-glycoprotein L complex is a major target for neutralizing monoclonal antibodies.},
  author={Michael B. Gill and Laurent Gillet and Susanna Colaco and J. Schm{\"a}hling May and Brigitte D. de Lima and Philip G Stevenson},
  journal={The Journal of general virology},
  year={2006},
  volume={87 Pt 6},
  pages={1465-75}
}
Herpesviruses characteristically persist in immune hosts as latent genomes, but to transmit infection they must reactivate and replicate lytically. The interaction between newly formed virions and pre-existing antibody is therefore likely to be a crucial determinant of viral fitness. Murine gammaherpesvirus-68 (MHV-68) behaves as a natural pathogen of conventional, inbred mice and consequently allows such interactions to be analysed experimentally in a relatively realistic setting. Here… CONTINUE READING

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