Murine Sirt3 protein isoforms have variable half-lives.


Sirt3 is a NAD+-dependent protein deacetylase mainly localized in mitochondria. Recent studies indicate that the murine Sirt3 gene expresses different transcript variants resulting in three possible Sirt3 protein isoforms with variable lengths at the N-terminus: M1 (aa 1-334), M2 (aa 15-334), and M3 (aa 78-334). In this study, we stably expressed these… (More)
DOI: 10.1016/j.gene.2011.07.029


Cite this paper

@article{Yang2011MurineSP, title={Murine Sirt3 protein isoforms have variable half-lives.}, author={Yongjie Yang and Ke Chen and Qiang Tong}, journal={Gene}, year={2011}, volume={488 1-2}, pages={46-51} }