Murine CD146 is widely expressed on endothelial cells and is recognized by the monoclonal antibody ME-9F1

@article{Schrage2008MurineCI,
  title={Murine CD146 is widely expressed on endothelial cells and is recognized by the monoclonal antibody ME-9F1},
  author={Arnhild Schrage and Christoph Loddenkemper and Ulrike Erben and Uta Lauer and Gert Hausdorf and Peter Jungblut and Judith P. Johnson and Percy A Knolle and Martin Zeitz and Alf Hamann and Katja Klugewitz},
  journal={Histochemistry and Cell Biology},
  year={2008},
  volume={129},
  pages={441 - 451}
}
The endothelium plays an important role in the exchange of molecules, but also of immune cells between blood and the underlying tissue. The endothelial molecule S-Endo 1 antigen (CD146) is preferentially located at endothelial junctions and has been claimed to support endothelial integrity. In this study we show that the monoclonal antibody ME-9F1 recognizes the extracellular portion of murine CD146. Making use of ME-9F1 we found CD146 highly expressed and widely spread on endothelial cells in… CONTINUE READING
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