Muramyl dipeptide improves mononuclear phagocyte system function in obstructive jaundice.

@article{Dunn1990MuramylDI,
  title={Muramyl dipeptide improves mononuclear phagocyte system function in obstructive jaundice.},
  author={Christopher W. Dunn and Jureta W. Horton},
  journal={The Journal of surgical research},
  year={1990},
  volume={48 3},
  pages={249-53}
}
Previous studies have demonstrated depression of the mononuclear phagocyte system (MPS) of which the liver comprises 80-85% in animals subjected to 21 days of obstructive jaundice. This study examined the ability of a macrophage stimulant, muramyl dipeptide (MDP), to reverse MPS dysfunction in an obstructive jaundice rat model. Sixty-two male Sprague-Dawley… CONTINUE READING