Muramyl dipeptide and IL-1 effects on sleep and brain temperature after inhibition of serotonin synthesis.

Abstract

The role of the interactions between serotonin (5-HT) and muramyl dipeptide (MDP) and interleukin-1 (IL-1) in sleep control and thermoregulation was evaluated. To this purpose, MDP and IL-1 were injected intracerebroventricularly at dark onset into freely moving rats pretreated twice intraperitoneally with para-chlorophenylalanine (PCPA) (300 mg/kg), which… (More)

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@article{Imeri1997MuramylDA, title={Muramyl dipeptide and IL-1 effects on sleep and brain temperature after inhibition of serotonin synthesis.}, author={Luca Imeri and Susanna Bianchi and Marisela D Mancia}, journal={The American journal of physiology}, year={1997}, volume={273 5 Pt 2}, pages={R1663-8} }