MurNAc -‐‐ pentapeptide Translocase and Ternary Complex

  title={MurNAc -‐‐ pentapeptide Translocase and Ternary Complex},
  author={Chih Pin and Chung and Seok and Yong Lee and Pei Zhou and Geoffrey and Pitt and Leonard D Spicer}
Phospho-MurNAc-pentapeptide translocase (MraY) is a conserved membrane-spanning enzyme involved in the biosynthesis of bacterial cell walls. MraY generates lipid I by transferring the phospho-MurNAc-pentapeptide to the lipid carrier undecaprenyl-phosphate. MraY is a primary target for antibiotic development because it is essential in peptidoglycan synthesis… CONTINUE READING