Mumps and ovarian cancer: modern interpretation of an historic association

@article{Cramer2010MumpsAO,
  title={Mumps and ovarian cancer: modern interpretation of an historic association},
  author={Daniel W Cramer and Allison F. Vitonis and Simone P. Pinheiro and John R. McKolanis and Raina Nakova Fichorova and Kevin E. Brown and Todd F. Hatchette and Olivera Olja J Finn},
  journal={Cancer Causes & Control},
  year={2010},
  volume={21},
  pages={1193-1201}
}
Epidemiologic studies found childhood mumps might protect against ovarian cancer. To explain this association, we investigated whether mumps might engender immunity to ovarian cancer through antibodies against the cancer-associated antigen MUC1 abnormally expressed in the inflamed parotid gland. Through various health agencies, we obtained sera from 161 cases with mumps parotitis. Sera were obtained from 194 healthy controls. We used an ELISA to measure anti-MUC1 antibodies and electro… CONTINUE READING