Multivariate determination of glucose in whole blood by attenuated total reflection infrared spectroscopy.

@article{Heise1989MultivariateDO,
  title={Multivariate determination of glucose in whole blood by attenuated total reflection infrared spectroscopy.},
  author={H Michael Heise and Ralf Marbach and G Janatsch and J{\"u}rgen D. Kruse-Jarres},
  journal={Analytical chemistry},
  year={1989},
  volume={61 18},
  pages={2009-15}
}
A spectral analysis of whole EDTA blood was undertaken by using attenuated total reflection and Fourier-transform infrared spectroscopy. The concentration of blood glucose was measured by an enzymatic method using glucose dehydrogenase and ranged between 40 and 290 mg/dL with an average concentration of 90.4 mg/dL. Multivariate calibration with the partial least-squares (PLS) algorithm was performed on spectral data between 1500 and 750 cm-1 showing a varying background from different… CONTINUE READING

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