Multivariate data analysis in biochemistry: a new integrative approach to metabolic control in brain aging.

@article{Giuliani1991MultivariateDA,
  title={Multivariate data analysis in biochemistry: a new integrative approach to metabolic control in brain aging.},
  author={Andrea Giuliani and Giorgio Capuani and Alfredo Miccheli and Tommaso Aureli and M T Ramacc and Franco Conti},
  journal={Cellular and molecular biology},
  year={1991},
  volume={37 6},
  pages={631-8}
}
The principal component analysis (PCA) allows to obtain a quantitative measure of the state of metabolism as a whole. In this paper we applied this method to the study of energy metabolism during aging process and of the effect of a drug (Acetyl-1-carnitine, ALCAR) on the aging brain.