Multivariate classification of patients with Alzheimer’s and dementia with Lewy bodies using high-dimensional cortical thickness measurements: an MRI surface-based morphometric study

@article{Lebedev2012MultivariateCO,
  title={Multivariate classification of patients with Alzheimer’s and dementia with Lewy bodies using high-dimensional cortical thickness measurements: an MRI surface-based morphometric study},
  author={Alexander V. Lebedev and Eric Westman and Mona K. Beyer and Milica Gregoric Kramberger and Cynthia Aguilar and Zvezdan Pirtosek and Dag Aarsland},
  journal={Journal of Neurology},
  year={2012},
  volume={260},
  pages={1104-1115}
}
Alzheimer’s disease (AD) and dementia with Lewy bodies (DLB) are the most common neurodegenerative dementia types. It is important to differentiate between them because of the differences in prognosis and treatment approaches. Investigate if sparse partial least squares (SPLS) classification of cortical thickness measurements could differentiate between AD and DLB. Two independent cohorts without MR-protocol alignment in Norway and Slovenia with 97 AD and DLB subjects were enrolled. Cortical… CONTINUE READING
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