Multivariate analysis of prognostic factors in fulminant hepatitis B

  title={Multivariate analysis of prognostic factors in fulminant hepatitis B},
  author={J. Bernuau and A. Goudeau and T. Poynard and F. Dubois and G. Lesage and B. Yvonnet and C. Degott and A. Bezeaud and B. Rueff and J. Benhamou},
  • J. Bernuau, A. Goudeau, +7 authors J. Benhamou
  • Published 1986
  • Medicine
  • Hepatology
  • We assessed prognostic factors in 115 patients with serologically defined fulminant hepatitis B. The diagnosis in each case was based on the finding of IgM antibody to the hepatitis B core antigen in serum. Multivariate analysis showed that factor V level (p < 0.001), patient's age (p = 0.001), absence of detectable HBsAg by radioimmunoassay (p = 0.06) and serum α‐fetoprotein concentration (p = 0.07) were independent predictors of survival. The survival rate in the 21 patients in whom HBsAg was… CONTINUE READING
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