Multivalent virus-like-particle vaccine protects against classic and variant infectious bursal disease viruses.

@article{Jackwood2013MultivalentVV,
  title={Multivalent virus-like-particle vaccine protects against classic and variant infectious bursal disease viruses.},
  author={Daral J. Jackwood},
  journal={Avian diseases},
  year={2013},
  volume={57 1},
  pages={41-50}
}
Nucleotide sequences that encode the pVP2 proteins from a variant infectious bursal disease virus (IBDV) strain designated USA08MD34p and a classic IBDV strain designated Mo195 were produced with the use of reverse-transcriptase-polymerase chain reaction (RT-PCR) and cloned into a pGEM-T Easy vector. A nucleotide sequence that encodes the VP3 protein was also produced from the USA08MD34p viral genome with the use of RT-PCR and cloned into a pGEM-T Easy vector. The VP3 and pVP2 clones were… CONTINUE READING