Multivalent Display of Antifreeze Proteins by Fusion to Self-Assembling Protein Cages Enhances Ice-Binding Activities.

@article{Phippen2016MultivalentDO,
  title={Multivalent Display of Antifreeze Proteins by Fusion to Self-Assembling Protein Cages Enhances Ice-Binding Activities.},
  author={Sean W Phippen and Corey A Stevens and Tyler D. R. Vance and Neil P. King and David P. Baker and Peter L Davies},
  journal={Biochemistry},
  year={2016},
  volume={55 49},
  pages={6811-6820}
}
Antifreeze proteins (AFPs) are small monomeric proteins that adsorb to the surface of ice to inhibit ice crystal growth and impart freeze resistance to the organisms producing them. Previously, monomeric AFPs have been conjugated to the termini of branched polymers to increase their activity through the simultaneous binding of more than one AFP to ice. Here… CONTINUE READING