Multitude of coronavirus variants found in the US - but the threat is unclear.

@article{Callaway2021MultitudeOC,
  title={Multitude of coronavirus variants found in the US - but the threat is unclear.},
  author={Ewen Callaway},
  journal={Nature},
  year={2021}
}
A PENNdemic Year in Review
Up State of the SARS-COV-2 Spike Homotrimer Favors an Increased Virulence for New Variants
TLDR
Analysis of possible molecular mechanisms responsible for the increased transmissibility and the increased rate of hospitalizations related to variants of SARS-CoV-2 showed that the increased virulence is more likely to be due to the improved stability to the S trimer in the opened state, rather than due to alterations in the complexation RBD-ACE2.
The Up state of the SARS-COV-2 Spike homotrimer favors an increased virulence for new variants
TLDR
Analysis of possible molecular mechanisms responsible for the increased transmissibility and the increased rate of hospitalizations related to variants of SARS-CoV-2 showed that the increased virulence is more likely to be due to the improved stability to the S trimer in the opened state than due to alterations in the complexation RBD-ACE2.
Towards an optimal monoclonal antibody with higher binding affinity to the receptor-binding domain of SARS-CoV-2 spike proteins from different variants
TLDR
Although the SARS-CoV-2 was specifically targeted in this work, the approach is generally suitable for many diseases and viral and bacterial pathogens, leukemia, cancer, multiple sclerosis, rheumatoid, arthritis, lupus, and more.
Depression Symptoms Mediate Mismatch Between Perceived Severity of the COVID-19 Pandemic and Preventive Motives
TLDR
Monitoring changes in beliefs about the coronavirus disease 2019 pandemic, depressive symptoms, and preventive motives between the first and second waves in South Korea highlighted the importance of psychological responses to the dynamically evolving pandemic situations in promoting preventive behaviors.
Review of COVID-19 Variants and COVID-19 Vaccine Efficacy: What the Clinician Should Know?
TLDR
Continuation of precautionary measures, genomic surveillance and vaccination plays an important role in the prevention of spread, early identification of variants, prevention of mutations and viral replication, respectively.
COVID-19 Surveillance Updates in US Metropolitan Areas: Dynamic Panel Data Modeling
TLDR
There is great variation in epidemiological curves across US metropolitan areas, including increasing numbers of new cases in 8 of the largest 25 metropolitan areas for the week ending September 19, 2021, strongly indicate the need for continued surveillance and perhaps a return to more restrictive public health guidelines for some areas.
Marginal cost of multiple nomenclature conventions for SARS-CoV-2 variants (Preprint)
TLDR
It is suggested that current collective propensities to contextualizing stigmas would result in social costs, without a one-size-fits-all nomenclature framework for SARS-CoV-2 variants.
Global variation in sequencing impedes SARS-CoV-2 surveillance
TLDR
Initial failure to extend this into the study of SARS-CoV-2 to track viral mutations and improve public health represents a troubling, self-inflicted barrier to battling Coronavirus Disease 2019.
SARS-CoV-2 variants: A double-edged sword?
TLDR
This review has highlighted major SARS-CoV-2 variants as well as other local strains along with their specific mutations, suspected changes in their characteristics, and their impact on the current pandemic and vaccine efficacy.

References

Estimation of secondary household attack rates for emergent SARS-CoV-2 variants detected by genomic surveillance at a community-based testing site in San Francisco
TLDR
The increase in prevalence, relative household attack rates, and reproductive number are consistent with a modest transmissibility increase of the "West Coast" variants; however, additional laboratory and epidemiological studies are required to better understand differences between these variants.