Multisystem inflammatory syndrome in children: A systematic review

@article{Ahmed2020MultisystemIS,
  title={Multisystem inflammatory syndrome in children: A systematic review},
  author={Mubbasheer Ahmed and Shailesh M. Advani and Axel Moreira and Sarah Zoretic and John Martinez and Kevin T. Chorath and Sebasti{\'a}n Acosta and Rija Naqvi and Finn Burmeister-Morton and Fiona Burmeister and Aina Tarriela and Matthew Petershack and Mary Evans and Ansel Hoang and Karthik Rajasekaran and Sunil K Ahuja and {\'A}lvaro Freitas Moreira},
  journal={EClinicalMedicine},
  year={2020},
  volume={26}
}
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Outcomes of multisystem inflammatory syndrome in children temporally related to COVID-19: a longitudinal study
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The outcome of multisystem inflammatory syndrome in children (MIS-C) temporally related to coronavirus disease 2019 (COVID-19) in a resource-limited setting is favorable in children without preexisting comorbidities.
Clinical and laboratory profile of multisystem inflammatory syndrome in children: A cross-sectional study in a tertiary care hospital, Mysuru
TLDR
Early recognition and prompt medical attention are necessary for a favorable outcome in MIS-C, however, there is scarcity of data regarding its long-term outcome.
Distinctive Phenotype of Multisystem Inflammatory Syndrome in Children Associated with SARS-CoV-2 According to Patients’ Age: A Monocentric Experience
TLDR
MIS-C is a new emerging condition and represents a challenge to pediatricians due to the severity of presentation and further studies to better characterize the long-term outcome of MIS-C patients are mandatory.
Multisystem Inflammatory Syndrome in Infants <12 months of Age, United States, May 2020-January 2021.
TLDR
Infants appear to have a milder course of MIS-C than older children with resolution of their illness after hospital discharge, and the full clinical picture across the pediatric age spectrum is evolving.
The emerging threat of multisystem inflammatory syndrome in adults (MIS-A) in COVID-19: A systematic review.
Multisystem inflammatory syndrome in children (MIS-C) related to COVID-19 infection in the state of Qatar: Association with Kawasaki-like Illness
TLDR
The authors' young children who presented with MIS-C related to SARS-CoV-2 infection had significantly higher Kawasaki-disease picture compared to other reports.
A systematic review on Multisystem Inflammatory Syndrome in Children (MIS-C) with COVID-19: Development of a scoring system for clinical diagnosis
TLDR
The children with COVID-19 having cardiac and/or gastrointestinal involvement are more likely to develop MIS-C and have higher mortality rates, and the scoring system developed herein will aid clinicians in patient diagnosis and timely management.
Severe Multi-inflammatory Syndrome in Children Temporally Related to COVID 19-Clinical Course, Laboratory Profile and Outcomes from a North Indian PICU.
TLDR
If disease progresses rapidly despite first line therapy (IvIg and steroids), use of Tocilizumab should be considered-as a rescue therapy under resource limitations in the absence of extracorporeal support.
Imaging findings of multisystem inflammatory syndrome in children associated with COVID-19
TLDR
Typical imaging findings in children with multisystem inflammatory syndrome associated with COVID-19 showed pulmonary, cardiac, abdominal and brain imaging findings, reflecting the multi-modal nature of this disease.
Cardiac manifestations and diagnostic imaging in pediatric inflammatory multisystem syndrome temporally associated with COVID-19: a systematic review
TLDR
This review found various cardiac abnormalities that may develop during PIMS-TS patients and should be more vigilant and not underestimate the consequences in pediatric COVID-19 patients.
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Multisystem inflammatory syndrome in children associated with SARS-CoV-2 led to serious and life-threatening illness in previously healthy children and adolescents.
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COVID-19 in 7780 pediatric patients: A systematic review
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