Multisystem Inflammatory Syndrome in Children Associated with COVID 19 Treated with Oral Steroid

  title={Multisystem Inflammatory Syndrome in Children Associated with COVID 19 Treated with Oral Steroid},
  author={Mukesh Kumar Jain and Sanjay Kumar Sahu and Jyoti Ranjan Behera and Sibabratta Patnaik},
  journal={Indian Journal of Pediatrics},
  pages={106 - 106}
To the Editor: Multisystem inflammatory syndrome in children (MIS-C) have been reported from various parts of the globe including India sharing clinical features with Kawasaki disease (KD) and toxic shock syndrome (TSS) [1]. World Health Organisation (WHO) and Centre for Disease Control and Prevention (CDC) have laid down case defining criteria for MIS-C separately [2, 3]. Antibody dependent enhancement (ADE) is the proposed pathogenesis leading to cytokine storm. Intravenous immunoglobulin… 

Multisystem Inflammatory Syndrome in Children Associated with COVID-19: An Interim Review

The prognosis is favorable with low mortality but meticulous cardiac monitoring and follow-up by a multidisciplinary team is very important, and future research may reveal different manifestations, newer diagnostic modalities, and better treatment options.

Cardiac Manifestations of Multisystem Inflammatory Syndrome in Children (MIS-C) Associated with SARS-CoV-2 Infection

Cardiac manifestations, including coronary and myocardial involvement, are common and should be carefully identified in children diagnosed with MIS-C and long-term follow-ups are required.

Eastern India Collaboration on Multisystem Inflammatory Syndrome in Children (EICOMISC): A Multicenter Observational Study of 134 Cases

  • Snehamayee NayakP. C. Panda Majhi Meher Poddar Sahoo Mohanty Padhy Nayak Dash Meher Subash Chandra Kumar Sitanshu Chandrakant Jyotipra
  • Medicine
    Frontiers in Pediatrics
  • 2022
Underlying co-morbidity, lymphopenia, thrombocytosis, hyponatremia, increased LDH, and hypoalbuminemia were the factors significantly associated with an increased mortality in MIS-C.

The Multifaceted Presentation of the Multisystem Inflammatory Syndrome in Children: Data from a Cluster Analysis

MIS-C is not a single disease presenting with various clinical features and outcomes and understanding the disease spectrum will provide individualized management, according to phenotypes of disease.

Multisystem Inflammatory Syndrome and Autoimmune Diseases Following COVID-19: Molecular Mechanisms and Therapeutic Opportunities

The molecular and pathophysiological mechanisms and therapeutic opportunities for multisystem inflammatory syndrome and autoimmune diseases following SARS-CoV-2 infection are discussed to provide a clear view for health care providers and researchers.

Progress in the Diagnosis and Treatment of COVID-19 in Children: A Review

This article will review epidemiological characteristics, the mechanism of action, variant characteristics, clinical manifestations, auxiliary examinations and treatment of children with COVID-19, in order to provide help for the diagnosis, treatment and research ofChildren with CO VID-19.

SARS-CoV-2–related MIS-C: A key to the viral and genetic causes of Kawasaki disease?

SARS-CoV-2 is the trigger of MIS-C, which suggests that other viruses may trigger different forms of Kawasaki disease, which would facilitate the discovery of inborn errors of immunity to viruses underlying Kawasaki Disease.



Multisystem Inflammatory Syndrome in Children in COVID-19 Pandemic

A 5-y-old boy from a COVID-19 hotspot area in India who presented with high grade fever, abdominal pain, diarrhea, bulbar conjunctivitis, edema and shock is reported, which describes the classical presentation of MIS-C which shares features similar to Kawasaki Disease.

Multisystem Inflammatory Syndrome with Features of Atypical Kawasaki Disease during COVID-19 Pandemic

The authors report a very similar case of 5-y-old boy from a COVID-19 hotspot area who presented in late April 2020 with acute febrile illness with abdominal pain and loose stools followed by shock, and was discharged after 6 d of hospital stay.

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    Multisystem inflammatory syndrome in children and adolescents with COVID-19. Scientific brief: World Health Organisation

      Multisystem inflammatory syndrome with features of atypical kawasaki disease during COVID - 19 pandemic Multisystem inflammatory syndrome in children in COVID - 19 pandemic

        Emergency preparedness and response: Health alert network

        • Centers for Disease Control and Prevention