Multistage designs in the genomic era: providing balance in complex disease studies.

@article{Dub2007MultistageDI,
  title={Multistage designs in the genomic era: providing balance in complex disease studies.},
  author={Marie-Pierre Dub{\'e} and Silke Schmidt and Elizabeth H Hauser and Hatef Darabi and Jing Li and Amina Barhdadi and Xuexia Wang and Quiying Sha and Zhaogong Zhang and Tao Wang and Hugues Aschard and Micka{\"e}l Guedj and Rori Rohlfs and Amy Anderson and Chelsea L Taylor and Lucia Mirea and Radoslav Nickolov and Valentin B. Milanov and Hsin-Chao Yang and Yeunjoo E. Song and Ritwik Sinha},
  journal={Genetic epidemiology},
  year={2007},
  volume={31 Suppl 1},
  pages={S118-23}
}
In this summary paper, we describe the contributions included in the Multistage Design group (Group 14) at the Genetic Analysis Workshop 15, which was held during November 12-14, 2006. Our group contrasted and compared different approaches to reducing complexity in a genetic study through implementation of staged designs. Most groups used the simulated dataset (problem 3), which provided ample opportunities for evaluating various staged designs. A wide range of multistage designs that targeted… CONTINUE READING