Multiscale model for the assessment of autonomic dysfunction in human endotoxemia.

@article{Foteinou2010MultiscaleMF,
  title={Multiscale model for the assessment of autonomic dysfunction in human endotoxemia.},
  author={Panagiota T. Foteinou and Steve E. Calvano and Stephen F. Lowry and Ioannis P. Androulakis},
  journal={Physiological genomics},
  year={2010},
  volume={42 1},
  pages={5-19}
}
Severe injury and infection are associated with autonomic dysfunction. The realization that a dysregulation in autonomic function may predispose a host to excessive inflammatory processes has renewed interest in understanding the role of central nervous system (CNS) in modulating systemic inflammatory processes. Assessment of heart rate variability (HRV) has been used to evaluate systemic abnormalities and as a predictor of the severity of illness. Dissecting the relevance of… CONTINUE READING

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