Multiscale biomimetic topography for the alignment of neonatal and embryonic stem cell-derived heart cells.

@article{Luna2011MultiscaleBT,
  title={Multiscale biomimetic topography for the alignment of neonatal and embryonic stem cell-derived heart cells.},
  author={Jesus Isaac Luna and Jes{\'u}s Ciriza and Marcos E. Garcia-Ojeda and Marco Kong and Anthony W. Herren and Deborah K Lieu and Ronald A. Li and Charless C. Fowlkes and Michelle Khine and Kara E McCloskey},
  journal={Tissue engineering. Part C, Methods},
  year={2011},
  volume={17 5},
  pages={579-88}
}
Nano- and microscale topographical cues play critical roles in the induction and maintenance of various cellular functions, including morphology, adhesion, gene regulation, and communication. Recent studies indicate that structure and function at the heart tissue level is exquisitely sensitive to mechanical cues at the nano-scale as well as at the microscale level. Although fabrication methods exist for generating topographical features for cell culture, current techniques, especially those… CONTINUE READING
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