Multipotent neural stem cells generate glial cells of the central complex through transit amplifying intermediate progenitors in Drosophila brain development.

@article{Viktorin2011MultipotentNS,
  title={Multipotent neural stem cells generate glial cells of the central complex through transit amplifying intermediate progenitors in Drosophila brain development.},
  author={Gudrun Viktorin and Nadia Riebli and Anna Popkov{\'a} and Angela Giangrande and Heinrich Reichert},
  journal={Developmental biology},
  year={2011},
  volume={356 2},
  pages={553-65}
}
The neural stem cells that give rise to the neural lineages of the brain can generate their progeny directly or through transit amplifying intermediate neural progenitor cells (INPs). The INP-producing neural stem cells in Drosophila are called type II neuroblasts, and their neural progeny innervate the central complex, a prominent integrative brain center. Here we use genetic lineage tracing and clonal analysis to show that the INPs of these type II neuroblast lineages give rise to glial cells… CONTINUE READING