Multipotent mesenchymal stem cells from amniotic fluid originate neural precursors with functional voltage-gated sodium channels.

@article{Mareschi2009MultipotentMS,
  title={Multipotent mesenchymal stem cells from amniotic fluid originate neural precursors with functional voltage-gated sodium channels.},
  author={Katia Mareschi and Deborah Rustichelli and Valentina Comunanza and Roberta De Fazio and Cristina Cravero and Giulia Morterra and Barbara Martinoglio and Enzo Medico and Emilio Carbone and Chiara Benedetto and Franca Fagioli},
  journal={Cytotherapy},
  year={2009},
  volume={11 5},
  pages={534-47}
}
BACKGROUND AIMS Amniotic fluid (AF) contains stem cells with high proliferative and differentiative potential that might be an attractive source of multipotent stem cells. We investigated whether human AF contains mesenchymal stem cells (MSC) and evaluated their phenotypic characteristics and differentiation potential in vitro. METHODS AF was harvested during routine pre-natal amniocentesis at 14-16 weeks of pregnancy. AF sample pellets were plated in alpha-minimum essential medium (MEM) with… CONTINUE READING
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